Clinical Trials Did Not Show Covid Shots Were “Safe and Effective”

The clinical trials conducted for Covid-19 vaccines, particularly the mRNA shots by Pfizer and Moderna. It critiques the perception of these vaccines being "safe and effective," arguing that trial outcomes do not support these claims.

1. Perspective of a Former Pharmaceutical Executive:

• The author, Sasha Latypova, shares her experience in pharmaceutical development, noting her concerns about the safety of mRNA vaccines.

• She highlights a sudden shift from a cautious approach to a more enthusiastic promotion of vaccines for wide public use, which raised her suspicion.

2. Misinterpretation of Terms:

• "Safe and effective" is described as a marketing phrase rather than a scientific conclusion.

• Clinical trials focused primarily on whether the vaccines could prevent infection, NOT on safety, transmission prevention, or adverse effects.

3. Endpoint of Clinical Trials:

• The trials had a narrow endpoint: the number of individuals who showed Covid symptoms and tested positive via PCR tests.

• Important aspects like vaccine safety and side effects were not considered in the trial results.

4. Design Flaws in Trials:

• The trials did not thoroughly include vulnerable populations, such as pregnant women and people with pre-existing conditions.

• The second and third phases of the trials were combined, and individuals with severe reactions were reported but largely ignored.

5. Manipulation of Results:

• Claims of "95% effectiveness" were based on relative risk rather than absolute risk, misleading the public regarding the actual benefits and risks.

• A Canadian analysis indicated that out of 927 confirmed Covid cases in the trials, most occurred in the unvaccinated group, leading to a skewed perception of effectiveness.

6. Public Misunderstanding:

• The nuances of clinical trial metrics and statistical interpretation were not effectively communicated, hindering informed public consent regarding vaccination.

The article concludes that the clinical trials for Covid-19 vaccines did not adequately address safety or efficacy in a comprehensive manner. The phrase "safe and effective" is considered misleading, following a narrative that emphasized prevention of infection without adequately reporting on the broader implications and potential risks of vaccination. The work calls attention to the need for better transparency and clearer public communication regarding the findings from vaccine trials. 

https://brownstone.org/articles/clinical-trials-did-not-show-covid-shots-were-safe-and-effective/