Immune imprinting occurs when previous exposures leave such a strong immune memory that the body continues to produce antibodies targeting the past experience.
People who have taken at least three doses of the original version of the COVID-19 mRNA vaccine have been strongly immune imprinted, a study by the University of Washington found.
Immune imprinting occurs when previous infections or vaccinations leave such a strong immune memory that the body continues to produce immune cells and antibodies targeting the previous immune experience-even when exposed to a new variant or vaccine.
" could be a problem if the person was unable to mount a useful immune response against a new variant," Dr. Stanley Perlman, an immunologist and microbiologist at the University of Iowa, told The Epoch Times.
Some people did produce new immune cells that recognized only XBB.1.
Another reason is that the mRNA vaccine creates a more robust immune imprinting effect than previously known vaccines.
"Inactivated vaccines induce a weaker immune response, so there is less opportunity for the response to be biased ," Dr. Perlman said.
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