The effectiveness of Moderna's COVID-19 vaccine against infection turns negative over time
- Against more recent strains, including the currently dominant BA.5, the effectiveness turned negative.
- Researchers with Moderna and Kaiser Permanente, which carried out the study, also found that people who received three Moderna doses were more likely to become infected compared to those who received just two doses.
The study was published ahead of peer review on medRxiv, a preprint server.
- Researchers reached the numbers after analyzing data from Kaiser Permanente Southern California
- While researchers did estimate that the vaccine remains protective against severe illness, they didn't separate the effectiveness estimates by time since vaccination
- The CDC continues to recommend vaccination for virtually every person aged 6 months or older
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